ACTs are crucial in the treatment of malaria because they offer several advantages over monotherapy. Artemisinin derivatives act rapidly against the malaria parasite, reducing the parasite load quickly. When combined with a partner drug that has a longer half-life, the overall treatment becomes more effective, and the risk of [drug resistance](https://) decreases. This combination approach ensures that any parasites not killed by the artemisinin component are eliminated by the partner drug.
