Egil Lien - Infectious Diseases

Author Information

Egil Lien is a prominent researcher affiliated with the Centre of Molecular Inflammation Research, Department of Clinical and Molecular Medicine at the Norwegian University of Science and Technology in Trondheim, Norway. He is also associated with the Program in Innate Immunity within the Department of Medicine, Division of Infectious Diseases and Immunology at UMass Medical School in Worcester, Massachusetts, USA. His work primarily focuses on inflammation and immunity, contributing significantly to the understanding of infectious diseases and immune responses.

Research Contributions

Egil Lien has made substantial contributions to the field of immunology and inflammation, particularly concerning cell death mechanisms and their roles in disease progression. His research, as reflected in his publications, covers a spectrum of topics including the roles of caspase-8 and RIPK1 kinase in mediating inflammation and cell death. His work on caspase-8 has explored its multifaceted roles in apoptosis, necroptosis, and pyroptosis, highlighting its importance as a molecular switch. Additionally, his studies on RIP1 kinase activity have elucidated its involvement in conditions like steatohepatitis and multiple sclerosis, offering insights into potential therapeutic targets for inflammatory diseases.

Aliases

Egil Lien is also known by the aliases E. Lien and E Lien in various academic publications and databases.

Publication and Citation Metrics

Metric	Value
Total Papers	177
Total Citations	22,585
h-index	62

Publications:

RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis

DOI: 10.1016/j.celrep.2021.109112

Year: 2021

Multiple roles of caspase‐8 in cell death, inflammation, and innate immunity

DOI: 10.1002/JLB.3MR0420-305R

Year: 2020

Faculty Opinions recommendation of Activity of caspase-8 determines plasticity between cell death pathways.

DOI: 10.3410/f.736896731.793569588

Year: 2020

Complement component C3 and the TLR co-receptor CD14 are not involved in angiotensin II induced cardiac remodelling.

DOI: 10.1016/j.bbrc.2020.01.018

Year: 2020

Author Correction: Caspase-8 mediates inflammation and disease in rodent malaria

DOI: 10.1038/s41467-020-19620-0

Year: 2020

Faculty Opinions recommendation of Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis.

DOI: 10.3410/f.736936768.793569589

Year: 2020

RIP1 kinase activity promotes steatohepatitis through mediating cell death and inflammation in macrophages.

DOI: 10.1038/s41418-020-00668-w

Year: 2020

Caspase-8 mediates inflammation and disease in rodent malaria

DOI: 10.1038/s41467-020-18295-x

Year: 2020

Inhibition of HSP90 and activation of HSF1 diminishes macrophage NLRP3 inflammasome activity in alcoholic liver injury.

DOI: 10.1111/acer.14338

Year: 2020

RIP1 kinase activity promotes steatohepatitis through mediating cell death and inflammation in macrophages

DOI: 10.1101/2020.01.07.895516

Year: 2020

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