What Types of Assays are Used in HTS for Infectious Diseases?
The assays used in HTS can be broadly categorized into:
1. Biochemical Assays: These involve isolated enzymes or biochemical pathways from pathogens. They are highly specific but may not always translate to cellular contexts. 2. Cell-Based Assays: These use live cells to provide a more accurate representation of how a compound will behave in a living organism. They can be used to study viral entry, replication, and cytopathic effects.
