Cytochrome P450 14α Demethylase - Infectious Diseases

Relevant Publications

Promising Antileishmanial Activity of Essential Oil: In Vitro and In Silico Studies.

Issue Release: 2024

Silver(I) complexes with voriconazole as promising anti-Candida agents.

Issue Release: 2024

Functional Plasticity, Redundancy, and Specificity of Lanosterol 14α-Demethylase in Regulating the Sensitivity to DMIs in .

Issue Release: 2024

Green Chemistry and In-silico Techniques for Synthesis of Novel Pyranopyrazole and Pyrazolo-pyrano-pyrimidine Derivatives as Promising Antifungal Agents.

Issue Release: 2024

Structural modeling of cytochrome P450 51 from a deep-sea fish points to a novel structural feature in other CYP51s.

Issue Release: 2023

Non-target biotransformation enzymes as a target for triazole-zinc mixtures.

Issue Release: 2023

Re-evaluation of sensitivity of Monilinia fructicola isolates to the DMI fungicide propiconazole in the Southeastern United States and investigation of the genetic element Mona.

Issue Release: 2023

Synthesis and Antifungal Evaluation of New Azole Derivatives against .

Issue Release: 2023

Status of Fungicide Resistance and Physiological Characterization of Tebuconazole Resistance in in Sichuan Province, China.

Issue Release: 2022

Design, Synthesis, and Evaluation of Novel 4-Chloropyrazole-Based Pyridines as Potent Fungicide Candidates.

Issue Release: 2022

Characterisation of CYP51 as a Drug Target Using as Host.

Issue Release: 2022

A Botybirnavirus Isolated from Confers Hypervirulence and Decreased Sensitivity of Its Host Fungus to Difenoconazole.

Issue Release: 2022

Potential dual inhibition of SE and CYP51 by eugenol conferring inhibition of Candida albicans: Computationally curated study with experimental validation.

Issue Release: 2022

Phase 3 study evaluating the safety and efficacy of oteseconazole in the treatment of recurrent vulvovaginal candidiasis and acute vulvovaginal candidiasis infections.

Issue Release: 2022

Design, synthesis and mechanistic study of new 1,2,4-triazole derivatives as antimicrobial agents.

Issue Release: 2021

Synthesis, Antifungal Activity, 3D-QSAR, and Molecular Docking Study of Novel Menthol-Derived 1,2,4-Triazole-thioether Compounds.

Issue Release: 2021

No Evidence of Resistance to Trifloxystrobin, Triflumizole, and Boscalid in Isolates From U.S. Commercial Apple Orchards.

Issue Release: 2021

Characterization of the Molecular Mechanisms of Resistance against DMI Fungicides in Populations from the Czech Republic.

Issue Release: 2021

In Silico Structural Modeling and Analysis of Interactions of Cytochrome P450 Monooxygenases CYP51s with Substrates and Azoles.

Issue Release: 2021

Design and Synthesis of New Antifungals Based on N-Un-substituted Azoles as 14α Demethylase Inhibitor.

Issue Release: 2021

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