Aerosol Generating Procedures - Infectious Diseases

What are Aerosol Generating Procedures?

Aerosol generating procedures (AGPs) are medical or surgical interventions that can result in the production of airborne particles (aerosols) from respiratory tract fluids. These aerosols can remain suspended in the air and potentially contain infectious agents, thereby increasing the risk of transmission of infectious diseases, particularly those affecting the respiratory system.

Why Are AGPs Significant in Infectious Diseases?

AGPs are significant because they can facilitate the airborne transmission of infectious diseases. This is especially critical in healthcare settings where procedures such as intubation, mechanical ventilation, and bronchoscopy are commonly performed. Pathogens like the influenza virus, Mycobacterium tuberculosis, and the SARS-CoV-2 virus responsible for COVID-19 can spread more easily during these procedures, posing a risk to healthcare workers and other patients.

Which Procedures Are Considered as AGPs?

Some of the commonly recognized AGPs include:
- Intubation and Extubation: Inserting or removing a tube from the trachea can produce aerosols.
- Bronchoscopy: A procedure that involves inserting a camera into the airways.
- Cardiopulmonary Resuscitation (CPR): Certain actions during CPR can aerosolize respiratory secretions.
- Suctioning: Removing secretions from the airway can generate aerosols.
- Non-invasive Ventilation: Methods such as CPAP or BiPAP without a secure airway can lead to aerosol dispersion.

How Can Healthcare Workers Protect Themselves During AGPs?

Healthcare workers must employ appropriate personal protective equipment (PPE) to mitigate the risks associated with AGPs. This includes the use of N95 respirators or higher-level respirators, face shields, gowns, and gloves. Additionally, performing these procedures in a negative pressure room, if available, helps contain aerosols and reduce the potential for airborne transmission.

What Are the Risks Associated with AGPs?

The primary risk associated with AGPs is the increased potential for the transmission of airborne infectious diseases. This can lead to outbreaks within healthcare facilities, affecting both staff and vulnerable patients. AGPs also pose challenges in terms of infection control, requiring stringent protocols to ensure safety.

How Have AGPs Been Managed During the COVID-19 Pandemic?

The COVID-19 pandemic has highlighted the importance of AGPs in the context of respiratory infectious diseases. During the pandemic, many healthcare systems prioritized the identification and management of AGPs to prevent nosocomial transmission of SARS-CoV-2. This included revising guidelines to minimize unnecessary AGPs, enhancing ventilation systems, and ensuring adequate supplies of PPE.

What Are the Guidelines for Performing AGPs Safely?

Healthcare organizations have established guidelines to perform AGPs safely, which include:
- Pre-procedure Assessment: Evaluate the necessity of the AGP and consider alternatives that minimize aerosol generation.
- Use of PPE: Ensure all involved staff are wearing appropriate PPE.
- Environmental Controls: Utilize airborne infection isolation rooms when possible.
- Post-procedure Protocols: Implement cleaning and disinfection protocols to reduce environmental contamination.

Are There Non-Medical Scenarios Considered as AGPs?

Though most AGPs occur in medical settings, some non-medical scenarios can also generate aerosols. These include activities like singing, shouting, or playing wind instruments, which have been scrutinized during the pandemic for their potential to spread respiratory pathogens in community settings.

What Future Research is Needed on AGPs?

Future research on AGPs should focus on:
- Quantifying Aerosol Production: Understanding the volume and infectious potential of aerosols generated during different procedures.
- Innovative Safety Measures: Developing new technologies or protocols to reduce aerosolization.
- Long-term Effects: Investigating the implications of prolonged exposure to AGPs on healthcare workers' health.
In conclusion, understanding and managing aerosol generating procedures is crucial in controlling the spread of infectious diseases, especially in healthcare settings. By adhering to safety protocols and continuing research, the risks associated with AGPs can be effectively mitigated.



Relevant Publications

Partnered Content Networks

Relevant Topics