Mikko R. J. Seppänen - Infectious Diseases

Author Information

Mikko R. J. Seppänen is a prominent researcher in the field of infectious diseases, with a specific focus on inborn errors of immunity. He is affiliated with the Rare Diseases Center at the Children's Hospital, University of Helsinki and Helsinki University Hospital in Finland, and also works at the Adult Immunodeficiency Unit within the Infectious Diseases, Inflammation Center at the same institutions. His work is instrumental in advancing the understanding and management of rare immunodeficiency disorders.

Research Contributions

Mikko R. J. Seppänen has made significant contributions to the understanding of inborn errors of immunity and their clinical manifestations. His research covers a range of topics, including the pulmonary manifestations in patients with immune deficiencies, the connection between genetic mutations like STAT3 and autoimmune conditions, and the characterization of immune responses in various conditions. His work also delves into the genetic underpinnings of immune disorders and their links to other diseases, such as leukemia and cardiovascular conditions.

Aliases

Mikko R. J. Seppänen is known by several aliases in the academic community, including Mikko Rj Seppänen, Mikko Seppänen, and M. Seppänen. These variations are often used interchangeably in publications and citations.

Publication and Citation Metrics

Metric	Value
Total Papers	73
Total Citations	2849
H-index	22

Publications:

Pulmonary manifestations in a cohort of patients with inborn errors of immunity: an 8-year follow-up study.

DOI: 10.15586/aei.v50i1.388

Year: 2022

STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological dysregulation of NKG2Dhi CD8 killer T cells

DOI: 10.1101/2022.02.11.480027

Year: 2022

Immune response to a conserved enteroviral epitope of the major capsid VP1 protein is associated with lower risk of cardiovascular disease

DOI: 10.1016/j.ebiom.2022.103835

Year: 2022

Overactive STAT3 drives accumulation of disease-associated CD21low B cells

DOI: 10.1101/2021.12.20.473595

Year: 2021

Inborn Errors of Immunity on the Island of Ireland – A Cross-Jurisdictional UKPID/ESID Registry Report

DOI: 10.21203/rs.3.rs-766566/v1

Year: 2021

Initial presenting manifestations in 16,486 patients with Inborn Errors of Immunity include infections and non-infectious manifestations.

DOI: 10.1016/j.jaci.2021.04.015

Year: 2021

IRF2BP2 Mutation Is Associated with Increased STAT1 and STAT5 Activation in Two Family Members with Inflammatory Conditions and Lymphopenia

DOI: 10.3390/ph14080797

Year: 2021

RhoG deficiency abrogates cytotoxicity of human lymphocytes and causes hemophagocytic lymphohistiocytosis.

DOI: 10.1182/blood.2020008738

Year: 2021

Characterization of the clinical and immunological phenotype and management of 157 individuals with 56 distinct heterozygous NFKB1 mutations.

DOI: 10.1016/j.jaci.2019.11.051

Year: 2020

A Family With A20 Haploinsufficiency Presenting With Novel Clinical Manifestations and Challenges for Treatment

DOI: 10.1097/RHU.0000000000001268

Year: 2020

What vaccinations should be considered?

How Does Direct Contact Transmission Occur?

What are MHC Genes?

Why are Serological Tests Important?

What are the challenges in controlling Plasmodium falciparum malaria?

What are the Treatment Options for Cervical Cancer?

What are the Advantages of HTS in Infectious Disease Research?

What Types of Surveillance Systems Exist?

What is the Role of the Zika Virus in Microcephaly?

How Do Retroviruses Infect Cells?

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