Sars Cov 2 Protease Inhibitors - Infectious Diseases

Relevant Publications

Psoralidin acts as a dual protease inhibitor against PL and M of SARS-CoV-2.

Issue Release: 2025

Development of small molecule non-covalent coronavirus 3CL protease inhibitors from DNA-encoded chemical library screening.

Issue Release: 2025

Dual Inhibitors of SARS-CoV-2 3CL Protease and Human Cathepsin L Containing Glutamine Isosteres Are Anti-CoV-2 Agents.

Issue Release: 2025

Virtual Screening Identifies Inhibitors of SARS-CoV-2 Main Protease through Pharmacophore and Similarity Approaches.

Issue Release: 2025

Machine learning-based QSAR and LB-PaCS-MD guided design of SARS-CoV-2 main protease inhibitors.

Issue Release: 2024

Computational discovery of dual potential inhibitors of SARS-CoV-2 spike/ACE2 and M: 3D-pharmacophore, docking-based virtual screening, quantum mechanics and molecular dynamics.

Issue Release: 2024

Characterization and noncovalent inhibition of the K63-deubiquitinase activity of SARS-CoV-2 PLpro.

Issue Release: 2024

3-Chymotrypsin-like Protease (3CLpro) of SARS-CoV-2: Validation as a Molecular Target, Proposal of a Novel Catalytic Mechanism, and Inhibitors in Preclinical and Clinical Trials.

Issue Release: 2024

Exploring Cannabinoids as Potential Inhibitors of SARS-CoV-2 Papain-like Protease: Insights from Computational Analysis and Molecular Dynamics Simulations.

Issue Release: 2024

Natural-Target-Mimicking Translocation-Based Fluorescent Sensor for Detection of SARS-CoV-2 PLpro Protease Activity and Virus Infection in Living Cells.

Issue Release: 2024

Discovery of a Highly Promising Disulfide Derivative Scaffold as Inhibitor of SARS-CoV-2 main protease.

Issue Release: 2024

Anti-SARS-CoV-2 Viral Activity of Sweet Potato Trypsin Inhibitor via Downregulation of TMPRSS2 Activity and ACE2 Expression In Vitro and In Vivo.

Issue Release: 2024

SARS-CoV-2 Main Protease Inhibitors That Leverage Unique Interactions with the Solvent Exposed S3 Site of the Enzyme.

Issue Release: 2024

New Pyrimidinone Bearing Aminomethylenes and Schiff Bases as Potent Antioxidant, Antibacterial, SARS-CoV-2, and COVID-19 Main Protease M Inhibitors: Design, Synthesis, Bioactivities, and Computational Studies.

Issue Release: 2024

High-Resolution Substrate Specificity Profiling of SARS-CoV-2 M; Comparison to SARS-CoV M.

Issue Release: 2024

Glycyrrhizic acid conjugates with amino acid methyl esters target the main protease, exhibiting antiviral activity against wild-type and nirmatrelvir-resistant SARS-CoV-2 variants.

Issue Release: 2024

Deciphering inhibitory activity of marine algae Ecklonia cava phlorotannins against SARS CoV-2 main protease: A coupled in-silico docking and molecular dynamics simulation study.

Issue Release: 2024

Cyclic β-amino acids improve the serum stability of macrocyclic peptide inhibitors targeting the SARS-CoV-2 main protease.

Issue Release: 2024

Alchemical Enhanced Sampling with Optimized Phase Space Overlap.

Issue Release: 2024

Exploiting Hydrophobic Amino Acid Scanning to Develop Cyclic Peptide Inhibitors of the SARS-CoV-2 Main Protease with Antiviral Activity.

Issue Release: 2024

What Is the Future of Research on Respiratory Droplets?

How Are Blood Tests Conducted?

Why is Hygiene Important in Infectious Diseases?

Where Are Culex Mosquitoes Found?

What is Malaria?

What Happens During an Inflammatory Response?

What are the Side Effects?

How Do Pathogens Utilize Fatty Acid Biosynthesis?

How Can Hygiene Practices be Implemented in Healthcare Settings?

How Does Transmission Occur?

Sars Cov 2 Protease Inhibitors - Infectious Diseases

Relevant Publications

Partnered Content Networks

Relevant Topics