Cyp3a4 Enzyme - Infectious Diseases

Relevant Publications

3D spheroid HepaRG and fluorescent biphasic tracer for CYP3A4-mediated antibiotic interaction monitoring in sepsis.

Issue Release: 2024

Metabolic transformation of cyclopiazonic acid in liver microsomes from different species based on UPLC-Q/TOF-MS.

Issue Release: 2024

Case report and literature review: management of Paxlovid (nirmatrelvir/ritonavir)-induced acute tacrolimus toxicity in a patient with systemic lupus erythematosus.

Issue Release: 2024

The Role of Intestinal Cytochrome P450s in Vitamin D Metabolism.

Issue Release: 2024

CYP3A4-Mediated Metabolic Activation and Cytotoxicity of Chlortoluron.

Issue Release: 2024

Hepatic OATP1B zonal distribution: Implications for rifampicin-mediated drug-drug interactions explored within a PBPK framework.

Issue Release: 2024

A Study on the Protective Impact of Resveratrol on Liver Damage in Rats with Obstructive Jaundice.

Issue Release: 2024

Development of a Physiologically Based Pharmacokinetic Population Model for Diabetic Patients and its Application to Understand Disease-drug-drug Interactions.

Issue Release: 2024

CYP3A4 inhibitors may influence the quantification of [I]I-FP-CIT SPECT scans.

Issue Release: 2024

Effects of two commonly used antidepressants amitriptyline and fluoxetine on the pharmacokinetics of abrocitinib in rats.

Issue Release: 2024

Adverse event signal mining and serious adverse event influencing factor analysis of fulvestrant based on FAERS database.

Issue Release: 2024

In vitro demonstration of antedrug mechanism of a pharmacokinetic booster to improve CYP3A4 substrates by CYP3A4-mediated metabolism inhibition.

Issue Release: 2024

PBPK modeling: What is the role of CYP3A4 expression in the gastrointestinal tract to accurately predict first-pass metabolism?

Issue Release: 2024

Embryonic exposure to flubendiamide induces hepatotoxicity in domestic chicks by altering drug-metabolizing enzymes, antioxidant status, and liver function.

Issue Release: 2024

Cadmium causes spleen toxicity in chickens by regulating mitochondrial unfolded protein response and nuclear receptors response.

Issue Release: 2024

The Impact of Baohuoside I on the Metabolism of Tofacitinib in Rats.

Issue Release: 2024

The acute toxic effect of Chinese medicine Fuzi is exacerbated in kidney yang deficiency mice due to metabolic difference.

Issue Release: 2024

Effectiveness and Safety of Different Oral Anticoagulants with P-glycoprotein/ CYP3A4 Inhibitors: A Network Meta-analysis.

Issue Release: 2024

Effects of Clarithromycin and Ketoconazole on FK506 Metabolism in Different CYP3A4 Genotype Recombinant Metabolic Enzyme Systems.

Issue Release: 2024

Effect of Age, Comedications, and CYP3A4/5 Polymorphisms on Perampanel Exposure in Chinese Pediatric Patients With Epilepsy.

Issue Release: 2024

What is the Importance of International Collaboration?

What Are Some Common Misconceptions About Monogamy and Infectious Diseases?

How Effective are HIV Antivirals?

How Do Pathogens Exploit Host Metabolic Pathways?

How is Herpes Transmitted?

How Reliable Are Blood Tests?

What Are the Limitations of Throat Swabs?

How Do X-rays Assist in Diagnosing Infections?

How is Co-Infection Diagnosed?

How Do Bacteria Become Resistant?

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