C580y - Infectious Diseases

Relevant Publications

Molecular markers of artemisinin resistance during falciparum malaria elimination in Eastern Myanmar.

Issue Release: 2024

The prevalence of Pfk13 polymorphism in malaria patients treated with artemisinin-based therapy: a systematic review and meta-analysis.

Issue Release: 2024

A Biotinylated cpFIT-PNA Platform for the Facile Detection of Drug Resistance to Artemisinin in .

Issue Release: 2024

Stage-specific pharmacodynamic chloroquine and pyronaridine action on artemisinin ring-stage resistant Kelch C580Y mutation correlates to hemozoin inhibition process.

Issue Release: 2024

Burden of Submicroscopic Plasmodium Infections and Detection of kelch13 Mutant Parasites in Military and Civilian Populations in Papua New Guinea.

Issue Release: 2024

Impact of different mutations on Kelch13 protein levels, ART resistance, and fitness cost in parasites.

Issue Release: 2024

Artemisinin-resistant Plasmodium falciparum Kelch13 mutant proteins display reduced heme-binding affinity and decreased artemisinin activation.

Issue Release: 2024

Genetic surveillance shows spread of ACT resistance during period of malaria decline in Vietnam (2018-2020).

Issue Release: 2024

Modified dosing schedule efficacy of fosmidomycin and clindamycin against murine malaria Plasmodium berghei.

Issue Release: 2024

Temporal and spatial dynamics of Plasmodium falciparum clonal lineages in Guyana.

Issue Release: 2024

Mutations in Plasmodium falciparum PfK13 dysregulates PI3K/AKT signalling pathway in Artemisinin Resistance.

Issue Release: 2024

What exactly does the PfK13 C580Y mutation in Plasmodium falciparum influence?

Issue Release: 2023

Multi-omics dissection of stage-specific artemisinin tolerance mechanisms in Kelch13-mutant Plasmodium falciparum.

Issue Release: 2023

Molecular insights into artemisinin resistance in Plasmodium falciparum: An updated review.

Issue Release: 2023

Molecular surveillance of Plasmodium falciparum drug-resistance markers in Vietnam using multiplex amplicon sequencing (2000-2016).

Issue Release: 2023

Application of loop-mediated isothermal amplification combined with lateral flow assay visualization of Plasmodium falciparum kelch 13 C580Y mutation for artemisinin resistance detection in clinical samples.

Issue Release: 2023

Distribution of Plasmodium falciparum K13 gene polymorphisms across transmission settings in Ghana.

Issue Release: 2023

FIT-PNAs as RNA-Sensing Probes for Drug-Resistant .

Issue Release: 2022

Plasmodium falciparum Kelch13 and its artemisinin-resistant mutants assemble as hexamers in solution: a SAXS data-driven modelling study.

Issue Release: 2022

Apicoplast ribosomal protein S10-V127M enhances artemisinin resistance of a Kelch13 transgenic Plasmodium falciparum.

Issue Release: 2022

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